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Director Shareholdings

22nd July 2013

The Company has been informed that on 22 July 2013 certain Directors of the Company purchased ordinary shares in the Company as follows:

Director

No. of Shares purchased

Price at which shares purchased

No. of shares held pursuant to transaction (% of ISC following transaction)

David Evans

30,000

31.8 pence

5,130,000

(2.6%)

Kate Cornish-Bowden

45,000

32.0 pence

45,000

(0.02%)


For Further Information:

Scancell Holdings Plc
Dr Richard Goodfellow, Joint CEO                     + 44 (0) 74 2323 0 497
Professor Lindy Durrant, Joint CEO

Cenkos Securities: 
Camilla Hume                     +44 (0) 20 7397 8900
Stephen Keys

FTI Consulting 
Simon Conway                   +44 (0) 20 7831 3113
Mo Noonan


About Scancell

Scancell is developing novel immunotherapies for the treatment of cancer based on its ImmunoBody® and Moditope™ technology platforms. Scancell’s first ImmunoBody®, SCIB1 is being developed for the treatment of melanoma and is in Phase 1/2 clinical trials. Preliminary evidence from Part 1 of the study showing that SCIB1 produced an immune response which might be associated with clinical benefit in patients with malignant melanoma was released in December 2012.

Scancell’s ImmunoBody® vaccines target dendritic cells and stimulate both parts of the cellular immune system; the helper cell system where inflammation is stimulated at the tumour site; and the cytotoxic T-lymphocyte or CTL response where immune system cells are primed to recognise and kill specific cells.
Scancell has also identified and patented a series of modified epitopes that stimulate the production of killer CD4 T cells that destroy tumours without toxicity. The Directors believe that the Moditope™ platform could play a major role in the development of safe and effective cancer immunotherapies in the future.

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